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Feature Article
Single-molecule covalent magnetic tweezers
Soham Chakraborty, Shubhasis Haldar
Trends in Biochemical Sciences (Technology of the month)
May, 2023
DOI:https://doi.org/10.1016/j.tibs.2023.05.002
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Single-molecule force spectroscopy (SMFS) technology enables us to study the heterogeneous nature of the biomolecules that are otherwise inaccessible by conventional ensemble approaches. In particular, magnetic tweezers, a widely-used SMFS technology, exert magnetic force and torque on the single biomolecules and allows us to study their dynamic changes and interactions.
Recent Publications
Please click on the graphics or DOI to find the articles.
Deep Chaudhuri and Shubhasis Haldar
Biochemistry (IF: 2.9); 2025
Unravelling Antibody-Induced Mechanical Stability of Antigen: Insights from Single-Molecule Studies
Soham Chakraborty, Shivam Pandit, Madhu Bhatt, Debojyoti Chowdhury, Suman Chakrabarty, Shubhasis Haldar
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Protein Science (IF: 8); 2025
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Debojyoti Chowdhury; Ayush Mistry; Debashruti Maity; Riti Bhatia; Shreyansh Priyadarshi; Simran Wadan; Soham Chakraborty; Shubhasis Haldar
Communications Biology (IF: 6.35); 2024
Deep Chaudhuri, Debojyoti Chowdhury, Soham Chakraborty, Madhu Bhatt, Ayush Mistry, Aakashdeep Dutta, Shubhasis Haldar
Nanoscale (IF: 6.7); 2024
DOI: https://doi.org/10.1039/D3NR00398A
Souradeep Banerjee, Debojyoti Chowdhury, Soham Chakraborty, Shubhasis Haldar
Protein Science (IF: 8); 2024
DOI https://doi.org/10.1002/pro.5068
Ayush Chandrakant Mistry, Debojyoti Chowdhury, Soham Chakraborty, Shubhasis Haldar
Trends in Biochemical Sciences (IF: 14.3); 2023
DOI:https://doi.org/10.1016/j.tibs.2023.10.009
Deep Chaudhuri, Souradeep Banerjee, Soham Chakraborty, Debojyoti Chowdhury, Shubhasis Haldar
Biomacromolecules (IF: 7); 2022
DOI: https://doi.org/10.1021/acs.biomac.2c00451
Soham Chakraborty, Deep Chaudhuri, Souradeep Banerjee, Madhu Bhatt, Shubhasis Haldar
Nature Communications Biology (IF: 6.4); 2022
DOI: https://doi.org/10.1038/s42003-022-03258-3
Soham Chakraborty, Deep Chaudhuri, Dyuti Chaudhuri, Vihan Singh, Souradeep Banerjee, Debojyoti Chowdhury, Shubhasis Haldar
Nanoscale (IF: 8.3); 2022
DOI https://doi.org/10.1039/D1NR07582A
Souradeep Banerjee, Ritika Nara, Soham Chakraborty, Debojyoti Chowdhury, Shubhasis Haldar
Frontiers in Cell and Developmental Biology (IF: 6.7); 2022
DOI: https://doi.org/10.3389/fcell.2022.852878
Preprints
01
Methotrexate-modulated talin-dynamics drives cellular mechanical phenotypes via YAP signalling
D Chowdhury, S Dhabal, M Bhatt, D Maity, S Chakraborty, S Priyadarshi, S Haldar
bioRxiv, 2023.04. 07.535979
02
S Chakraborty, M Bhatt, D Chowdhury, D Chaudhuri, S Haldar
bioRxiv, 2022.04. 04.486950
Other selected articles
DsbA is a redox-switchable mechanical chaperone
EC Eckels, D Chaudhuri, S Chakraborty, DJ Echelman, S Haldar
Chemical Science 12 (33), 11109-11120
Protein folding modulates the chemical reactivity of a Gram-positive adhesin
Alvaro Alonso-Caballero, Daniel J Echelman, Rafael Tapia-Rojo, Shubhasis Haldar, Edward C Eckels, Julio M Fernandez
Nature Chemistry 13 (2), 172-181
Cutting-edge single-molecule technologies unveil new mechanics in cellular biochemistry
Souradeep Banerjee, Soham Chakraborty, Abhijit Sreepada, Devshuvam Banerji, Shashwat Goyal, Yajushi Khurana, Shubhasis Haldar
Annual Review of Biophysics 50, 419-445
Force-directed “Mechanointeractome” of talin–integrin
S Chakraborty, S Banerjee, M Raina, S Haldar
Biochemistry 58 (47), 4677-4695
Trigger factor chaperone acts as a mechanical foldase
S Haldar, R Tapia-Rojo, EC Eckels, J Valle-Orero, JM Fernandez
Nature communications 8 (1), 668